Recombinant Human IL-17F,BR

Known as:Interleukin-17F; IL-17F; Cytokine ML-1; Interleukin-24; IL-24; IL17F; IL24
Derived from:Human Cells
Purity:Greater than 95% as determined by reducing SDS-PAGE.
Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Storage:Lyophilized protein should be stored at < -20°c,="" though="" stable="" at="" room="" temperature="" for="" 3="" weeks.reconstituted="" protein="" solution="" can="" be="" stored="" at="" 4-7°c="" for="" 2-7="" days.aliquots="" of="" reconstituted="" samples="" are="" stable="" at="">< -20°c="" for="" 3="">
Reconstitution:Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin:Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background:Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6, IL-8, and granulocyte colony-stimulating factor. IL-17F can regulate cartilage matrix turnover and stimulates PBMC and T-cell proliferation. IL-17F is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Defects in IL-17F are the cause of familial candidiasis type 6 (CANDF6).
规格:10ug, 50ug, 500ug, 1mg, 注意：
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