Recombinant Human Complement Component C5a/C5a,BR

别名： Complement C5;C5a anaphylatoxin;C5a
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

背景说明： Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins.C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 α-chain.Human C5a has four α-helices plus three intrachain disulfide bonds that create a triple loop structure.Human C5a is 60% and 54% aa identical to mouse and rat C5a，respectively.C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2.Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation.It also triggers an oxidative burst in macrophages and neutrophils，and induces release of histamine in basophils and mast cells.
来源： E.coli

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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