Anti-NOTCH4 Polyclonal Antibody,BR

英文名称： Anti-NOTCH4 Polyclonal Antibody
中文名称： 跨膜蛋白NOTCH4配体抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Mouse ; Human
应用： IF ; WB
稀释比例： WB 1:100-500. IF 1:50-200.

靶标： NOTCH4
别名： Notch 4,FLJ16302, hNotch 4, hNotch4, INT 3, INT3, MGC74442, Neurogenic locus notch homolog protein 4, NOTC4_HUMAN, NOTCH 3, NOTCH 4, Notch 4 intracellular domain, Notch homolog 4, NOTCH3, Notch4, NOTCH4 protein,
背景说明： This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Swiss Prot： Q99466
Gene ID： 4855
亚细胞定位： Cell membrane Nucleus Single-pass type I membrane protein
免疫原： Recombinant protein of human NOTCH4
Public Immunogen Range： 1824-2003aa
理论分子量： 210kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。