Anti-PABPC4 Polyclonal Antibody,BR

英文名称： Anti-PABPC4 Polyclonal Antibody
中文名称： 多聚腺苷酸结合蛋白4抗体
规格： 100ul ; 50ul
宿主： Rabbit
克隆类型： Polyclonal Antibody
亚型： IgG
交叉反应：： Rat ; Human ; Mouse
应用： IF ; IHC ; WB
稀释比例： WB 1:500-2000. IHC 1:50-200. IF 1:50-200.

靶标： PABPC4
别名： Activated platelet protein 1, Activated-platelet protein 1, APP 1, APP-1, APP1, FLJ43938, Inducible poly(A) binding protein, Inducible poly(A)-binding protein, IPABP, IPABP4, PABP 4, PABP-4, PABP4, PABP4_HUMAN, PABPC 4, PABPC4, Poly A binding protein cytoplasmic 4, Poly(A) binding protein 4, Poly(A) binding protein cytoplasmic 4 (inducible form), Poly(A) binding protein cytoplasmic 4, Poly(A)-binding protein 4, Polyadenylate binding protein 4, Polyadenylate-binding protein 4, Polyadenylate-binding protein, cytoplasmic, 4, Polyadenylate-binding protein, inducible
背景说明： Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swiss Prot： Q13310
Gene ID： 8761
亚细胞定位： Cytoplasm
免疫原： A synthetic peptide of human PABPC4
Public Immunogen Range： 350-450aa
理论分子量： 71kDa

纯化方法： Affinity purification
储存液： PBS with 0.02% sodium azide，50% glycerol，pH7.3.
储存条件： Store at -20℃. Avoid freeze/thaw cycles.

使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

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